The Double-Edged Sword: Naloxone-Induced Noncardiogenic Pulmonary Edema

Naloxone-induced noncardiogenic pulmonary edema (NCPE) is a scarcely reported side effect that can occur after naloxone administration. We present case of 46-year-old male who presented to the emergency department for further management an opioid overdose, developed acute hypoxic respiratory failure several doses naloxone. The rapid deterioration patient’s status required increased supplemental oxygen, with plane film radiography suggesting diffuse edema. This emphasizes importance understanding significant effects lifesaving drug and implications they carry now available without prescription.