The Dombrock system: linkage relations with other blood group loci.

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The Dombrock system: linkage relations with other blood group loci.

The recognition of the blood group system called Dombrock was reported in 1965 by Swanson and her colleagues. In 1967 Tippett gave an account of the genetics of the system which included an analysis of the linkage relations of the Do locus to other blood group loci, based on families tested in the MRC Blood Group Unit up to April 1966. The present account brings the linkage analysis up to the e...

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In April I965, anti-Doa, an antibody defining a 'new' red cell antigen, was reported (Swanson, Polesky, Tippett, and Sanger, I965). The present paper records the results of tests with anti-Doa on samples received in this unit from October I964 until April I966. Anti-Doa reacts best by the antiglobulin test on papainized cells, but only a minority of otherwise good antiglobulin sera are suitable...

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Complexities of the Dombrock blood group system revealed.

The Do(a) antigen was discovered after I began my career in immunohematology and I have been fortunate to be involved in several fascinating discoveries in the Dombrock blood group system. The Do(a) antigen and its antithetical antigen, Do(b), have a prevalence that makes them useful as genetic markers. The paucity of reliable anti-Do(a) and anti-Do(b) has prevented this potential from being re...

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The incidence of spontaneous abortion in mothers with blood group O compared with other blood types

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the incidence of spontaneous abortion in mothers with blood group o compared with other blood types

although abo incompatibility between mother and fetus has long been suspected as cause of spontaneous abortion in man, its precise contribution has not been completely resolved. in spite of reports in which the incompatible mating was recognized to be a cause of habitual abortion, and which eventually results in infertility or a reduction in the number of living children compared with the numbe...

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ژورنال

عنوان ژورنال: Journal of Medical Genetics

سال: 1972

ISSN: 1468-6244

DOI: 10.1136/jmg.9.4.392