The Chick Embryo Chorioallantoic Membrane as a Model for in vivo Research on Anti-Angiogenesis
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چکیده
منابع مشابه
Evaluating the Effects of Enrofloxacin on Angiogenesis Using the Chick Embryo Chorioallantoic Membrane Model
Objective- Because little information was available in the literature about the angiogenic property of enrofloxacin, this investigation was undertaken to evaluate this aspect using an in vivomodel. Design- Experimental study. Animals- Twenty fertile chicken eggs (Ross 308) with the average egg-weight of 55 ± 0.4 g were rand...
متن کاملEvaluating the Effects of Enrofloxacin on Angiogenesis Using the Chick Embryo Chorioallantoic Membrane Model
ObjectiveBecause little information was available in the literature about the angiogenic property of enrofloxacin, this investigation was undertaken to evaluate this aspect using an in vivo model. DesignExperimental study. AnimalsTwenty fertile chicken eggs (Ross 308) with the average egg-weight of 55 ± 0.4 g were randomly divided into experimental and control groups. ProceduresAgar pellets wer...
متن کاملThe chick embryo chorioallantoic membrane (CAM). A multifaceted experimental model
During avian development the mesodermal layers of the allantois and chorion fuse to form the chorioallantoic membrane (CAM). This structure rapidly expands generating a rich vascular network that provides an interface for gas and waste exchange. The CAM allows to study tissue grafts, tumor growth and metastasis, wound healing, drugs delivery and toxicologic analysis, and angiogenic and anti-ang...
متن کاملThe chick embryo chorioallantoic membrane as a model for tumor biology.
Among the in vivo models, the chick embryo chorioallantoic membrane (CAM) has been used to implant several tumor types as well as malignant cell lines to study their growth rate, angiogenic potential and metastatic capability. This review article is focused on the major compelling literature data on the use of the CAM to investigate tumor growth and the metastatic process.
متن کاملEffects of antibodies to EG-VEGF on angiogenesis in the chick embryo chorioallantoic membrane.
BACKGROUND Endocrine gland-related vascular endothelial growth factor (EG-VEGF), is an angiogenic factor specifically targeting endothelial cells derived from endocrine tissues. The inhibition of the EG-VEGF/prokineticin receptor pathway could represent a selective antiangiogenic and anticancer strategy. AIM to evaluate the impact of an antibody to EG-VEGF on the rapidly growing capillary ple...
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ژورنال
عنوان ژورنال: Current Pharmaceutical Biotechnology
سال: 2000
ISSN: 1389-2010
DOI: 10.2174/1389201003379040