The biosynthesis of monoterpenoid indole alkaloids from strictosidine
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منابع مشابه
The Biosynthesis of Monoterpenoid lndole Alkaloids from Strictosidine
The differential incorporation of doubly labelled strictosidine and vincoside into several indole alkaloids belonging to the Corynanthe (3a and 3p series), Aspidosperma, and lboga types in three plant families has been studied, and it has been demonstrated that only strictosidine is incorporated while vincoside is metabolically inert in these plants with regard to alkaloid formation. During the...
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Strictosidine beta-D-glucosidase (SG) follows strictosidine synthase (STR1) in the production of the reactive intermediate required for the formation of the large family of monoterpenoid indole alkaloids in plants. This family is composed of approximately 2000 structurally diverse compounds. SG plays an important role in the plant cell by activating the glucoside strictosidine and allowing it t...
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There has been enormous progress over the past fifteen years or so in our understanding of the ways in which complex natural products are synthesized in living systems. In the field of alkaloids, as elsewhere, research during the initial phase1 pin-pointed those substances which are used as the common building blocks, examples being acetic acid, ornithine and lysine for the reduced systems, and...
متن کاملRigorous biogenetic network for a group of indole alkaloids derived from strictosidine.
Strictosidine, the precursor of more than 2,500 indole alkaloids, was isolated from four species of three plant families. By searching the Dictionary of Natural Products on DVD it was found that about 150 indole alkaloids were obtained from the same species (coalkaloids), which is a direct proof of their common origin. On the base of their three-dimensional structure, taxonomic properties and s...
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Phytochemical investigation of the 70% EtOH extract of the leaves of Alstonia scholaris afforded seven new monoterpenoid indole alkaloids: scholarisins I-VII (1-7), and three known compounds: (3R,5S,7R,15R,16R,19E)-scholarisine F (8), 3-epi-dihydro- corymine (9), and (E)-16-formyl-5α-methoxystrictamine (10). Structural elucidation of all the compounds was accomplished by spectral methods such a...
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ژورنال
عنوان ژورنال: J. Chem. Soc., Perkin Trans. 1
سال: 1979
ISSN: 0300-922X,1364-5463
DOI: 10.1039/p19790002308