Targeting the Gut Microbiome as a Treatment for Primary Sclerosing Cholangitis: A Conceptional Framework
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چکیده
منابع مشابه
Gut Inflammation in Primary Sclerosing Cholangitis and Autoimmune Sclerosing Cholangitis-Contrasting Pattern of Liver-gut Cross Talk
Article history: Received 27 September 2015 Accepted 27 September 2015 Available online 30 September 2015 histologicallymild, the patients had comparable fecal calprotectin levels as patients with IBD alone. However, the findings in the small bowel on capsule endoscopy were different between these entities. Seven of the capsule endoscopy studies in the patients with AISC were abnormal with muco...
متن کاملPrimary sclerosing cholangitis as an intractable disease.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown origin which eventually results in liver cirrhosis. The disease is reported to be more common among the Western population than in the Asian population. Asian experience remains limited. Diagnosis and treatment standards in the Far East have largely followed those in the West, including liver transplantation....
متن کاملPrimary sclerosing cholangitis
Primary sclerosing cholangitis (PSC) is a chronic inflammatory disorder of the biliary system that results in progressive fibrosis and strictures of the intrahepatic and extrahepatic bile ducts. Typical radiological changes on retrograde cholangiography are shown in Figure 1. These strictures cause cholestatic liver disease that may progress to end-stage cirrhosis. The disorder has a strong ass...
متن کاملPrimary Sclerosing Cholangitis: Introduction
The prevalence of primary sclerosing cholangitis in the United States is approximately 1–6 cases per 100,000 population. Most patients with primary sclerosing cholangitis are men (75%) with an average age of approximately 40 years at diagnosis. The overwhelming majority of patients affected with primary sclerosing cholangitis are Caucasian. The etiology is unknown but current opinion favors an ...
متن کاملPrimary sclerosing cholangitis.
PRIMARY sclerosing cholangitis, stenosing cholangitis, fibrosing cholangitis, chronic obliterative cholangitis are all terms referring to a rare diffuse type ofchronic inflammation of the entire common bile duct and at times of the hepatic ducts and their radicles. In most instances, sclerosing cholangitis is idiopathic or primary. Bartholomew et al., in 1963 found only twenty unequivocal cases...
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ژورنال
عنوان ژورنال: American Journal of Gastroenterology
سال: 2020
ISSN: 0002-9270,1572-0241
DOI: 10.14309/ajg.0000000000000604