Susceptibility of Candida glabrata biofilms to echinocandins: alterations in the matrix composition
نویسندگان
چکیده
منابع مشابه
Silver colloidal nanoparticles: effect on matrix composition and structure of Candida albicans and Candida glabrata biofilms.
AIM The aim of this study was to assess the effect of different silver nanoparticles (SN) concentrations on the matrix composition and structure of Candida albicans and Candida glabrata biofilms. METHODS AND RESULTS Candida biofilms were developed in 6-well microtiter plates during 48 h. After, these biofilms were exposed to 13.5 or 54 μg SN ml(-1) for 24 h. Then, extracellular matrices were ...
متن کاملFrequency of decreased susceptibility and resistance to echinocandins among fluconazole-resistant bloodstream isolates of Candida glabrata.
The echinocandin class of antifungal agents is considered to be the first-line treatment of bloodstream infections (BSI) due to Candida glabrata. Recent reports of BSI due to strains of C. glabrata resistant to both fluconazole and the echinocandins are of concern and prompted us to review the experience of two large surveillance programs, the SENTRY Antimicrobial Surveillance Program for the y...
متن کاملSusceptibility of Candida albicans and Candida glabrata biofilms to silver nanoparticles in intermediate and mature development phases.
PURPOSE The aim of this study was to investigate the susceptibility of Candida albicans and Candida glabrata biofilm development, in their intermediate and maturation stages, to the influence of silver nanoparticles (SN). METHODS SN (5 nm) suspensions were synthesized via reduction of silver nitrate by a solution of sodium citrate. These suspensions were used to treat Candida biofilms for fiv...
متن کاملReduced biocide susceptibility in Candida albicans biofilms.
Candida biofilm formation is common during infection and environmental growth. We tested the impacts of three biocides (ethanol [EtOH], H(2)O(2), and sodium dodecyl sulfate) on Candida albicans, C. parapsilosis, and C. glabrata biofilms. Higher concentrations of the biocides were required for efficacy against biofilms than for efficacy against planktonic controls. A combination study with two b...
متن کاملBiofilms of non-Candida albicans Candida species: quantification, structure and matrix composition.
Most cases of candidiasis have been attributed to C. albicans, but recently, non- Candida albicans Candida (NCAC) species have been identified as common pathogens. The ability of Candida species to form biofilms has important clinical repercussions due to their increased resistance to antifungal therapy and the ability of yeast cells within the biofilms to withstand host immune defenses. Given ...
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ژورنال
عنوان ژورنال: Biofouling
سال: 2018
ISSN: 0892-7014,1029-2454
DOI: 10.1080/08927014.2018.1472244