Sudden Cardiac Death With Apparently Normal Heart

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Sudden cardiac death with apparently normal heart.

BACKGROUND Mechanisms of sudden cardiac death (SCD) in subjects with apparently normal hearts are poorly understood. In survivors, clinical investigations may not establish normal cardiac structure with certainty. Large autopsy series may provide a unique opportunity to confirm structural normalcy of the heart before reviewing a patient's clinical history. METHODS AND RESULTS We identified an...

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Sudden cardiac death in young people with apparently normal heart.

OBJECTIVE The aim of the present study was to assess the prevalence of subtle morphologic substrates, clinically unrecognizable, underlying sudden cardiac death (SCD) in young people with apparently normal heart. METHODS In the time interval 1979--1998, 273 consecutive cases of SCD in young people (< or =35 years) which occurred in the Veneto Region of Italy were prospectively studied. Follow...

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Sudden cardiac death with normal heart: molecular autopsy.

Several culprits may be identified at postmortem in sudden death (SD) victims, including coronary artery, myocardial, valve, conduction system, and congenital heart diseases. However, particularly in young people, the heart can be found grossly and histologically normal in a not-so-minor amount of cases (the so-called unexplained SD or "mors sine materia") and inherited ion channel diseases are...

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Predicting sudden cardiac death in heart failure.

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An association between the anatomic pathology and pathophysiology of coronary atherosclerosis and sudden cardiac death (SCD) has been long recognized. At the end of the 15th century, Da Vinci described a personally witnessed SCD that he attributed to a “parched and shrunk and withered ... artery that feeds the heart” at autopsy,1 and in 1812, Warren, commenting on the significance of Heberden’s...

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ژورنال

عنوان ژورنال: Circulation

سال: 2000

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.102.6.649