منابع مشابه
The Effect of Temperature, pH, and Different Solubilizing Agents on Stability of Taxol
Inabilities to attain adequate aqueous solubility and stability have made the preparation of a clinically suitable formulation of taxol difficult. Addition of nicotinamide (ND), 2-hydroxypropyl- b-cyclodextrin (HPßCD), polyethylene glycol, (PEG), bile salts (BS, 50:50 sodium cholate: deoxycholate...
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A set of Xanthohumol derivatives were selected and molecular docking studies of these compounds on thioredoxin reductase were conducted. Based on new structural patterns using in silico-screening study, new potent lead compounds were designed. The results due to validated docking protocols lead to find that Thr58, Gly57, Gly21, Asp334, Glu163, Ala130, IIe332, Val44 and Gly132 are the main a...
متن کاملSurvival of phosphate-solubilizing bacteria against DNA damaging agents.
Phosphate-solubilizing bacteria (PSBs) were isolated from different plant rhizosphere soils of various agroecological regions of India. These isolates showed synthesis of pyrroloquinoline quinone (PQQ), production of gluconic acid, and release of phosphorus from insoluble tricalcium phosphate. The bacterial isolates synthesizing PQQ also showed higher tolerance to ultraviolet C radiation and mi...
متن کاملVIII. The Effect of Acidifying Agents on Susceptibility to Infection †
The experiments to be described were conducted with the aim of testing the suggestion of Beeson and Rowley,' that the peculiar susceptibility of the kidney to certain forms of bacterial infection may be dependent on local inactivation of complement by ammonia which is produced in renal tubular cells. This was based on the finding that kidney tissue has a considerably stronger anticornplementary...
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We have previously reported on the tumor inhibitory properties of 5-fluorouracil and 5-fluoroorotic acid (3, 4), prepared by Duschinsky et al. (5), and on the initial clinical trials of 5fluorouracil with patients with far advanced solid tumors (6). The metabolism of 5-fluorouracil and 5-fluororotic acid has been studied, data on excretion and tissue distribution in mice and man have been repor...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1961
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.81.8_1208