Studies on Diphenyl Disulfide Derivatives I

Studies on nicotinamide derivatives.

Experimental studies on carbon disulfide poisoning.

Anticancer Studies of Novel 2 , 4 - Disubstituted - 1 , 5 - Diphenyl - 1 H - Imidazole Derivatives

In the present work a series of novel 2,4-disubstituted -1, 5 -diphenyl substituted -1H-imidazole derivatives were screened for anticancer activity using human liver cancer cell line. Derivatives were evaluated for anticancer activities against Hep G2 (Human liver cancer) cell lines. Newly synthesized compounds A-IVn, A-IVo,B-IVb, B-IVc, B-IVd, and B-IVe showed highly significant cytotoxic acti...

Synthesis, crystal structures and docking studies of 2,7-diphenyl-1,4-diazepan-5-one derivatives

BACKGROUND 1,4-Diazepine derivatives are the seven membered, nitrogen containing heterocyclic ring systems possessing a wide range of therapeutic applications. 1,4-Diazepines attracted the attention of chemists and druggists due to their biological and medicinal properties, such as antimicrobial, anti-HIV and anticancer activities. Herein, we report the preparation, crystal structure determined...

Studies on the antigenic structure of ribonuclease. I. General role of hydrogen and disulfide bonds.

Studies of protein structure have reached a stage at which chemical configuration should shortly be correlated with biological activity. Although important advances have been made in describing the antigenic structure of polysaccharides (la, 2), little progress has been made in elucidating the antigenic structure of native proteins. Reagents that modify certain types of groups on proteins have ...