Streptococcus suis and group B Streptococcus differ in their interactions with murine macrophages
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چکیده
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Group B Streptococcus induces apoptosis in macrophages.
Group B Streptococcus (GBS) is a pathogen that has developed some strategies to resist host immune defenses. Because phagocytic killing is an important pathogenetic mechanism for bacteria, we investigated whether GBS induces apoptosis in murine macrophages. GBS type III strain COH31 r/s (GBS-III) first causes a defect in cell membrane permeability, then at 24 h, apoptosis. Apoptosis was confirm...
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Citation: Roy D, Takamatsu D, Okura M, Goyette-Desjardins G, Van Calsteren M-R, Dumesnil A, Gottschalk M and Segura M (2018) Capsular Sialyltransferase Specificity Mediates Different Phenotypes in Streptococcus suis and Group B Streptococcus. Front. Microbiol. 9:545. doi: 10.3389/fmicb.2018.00545 Capsular Sialyltransferase Specificity Mediates Different Phenotypes in Streptococcus suis and Grou...
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Streptococcus suis capsular type 2 is an important etiological agent of swine meningitis, and it is also a zoonotic agent. Since one hypothesis of the pathogenesis of S. suis infection is that bacteria enter the bloodstream and invade the meninges and other tissues in close association with mononuclear phagocytes, the objective of the present study was to evaluate the capacity of S. suis type 2...
متن کاملGroup A Streptococcus encounters with host macrophages.
Group A Streptococcus (GAS) is a leading human bacterial pathogen with diverse clinical manifestations. Macrophages constitute a critical first line of host defense against GAS infection, using numerous surface and intracellular receptors such as Toll-like receptors and inflammasomes for pathogen recognition and activation of inflammatory signaling pathways. Depending on the intensity of the GA...
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ژورنال
عنوان ژورنال: FEMS Immunology and Medical Microbiology
سال: 1998
ISSN: 0928-8244
DOI: 10.1016/s0928-8244(98)00048-0