منابع مشابه
Sorting Out Small RNAs
Small RNAs carry out their functions by guiding Argonaute (AGO) proteins to their targets. Diverse types of small RNAs and multiple AGO proteins exist in most eukaryotic species, but how small RNAs are sorted into specific AGO complexes remains unclear. Two papers in this issue (Mi et al., 2008; Montgomery et al., 2008) now reveal the importance of the 5' terminal nucleotide of the small RNA in...
متن کاملSorting of Drosophila Small Silencing RNAs
In Drosophila, small interfering RNAs (siRNAs), which direct RNA interference through the Argonaute protein Ago2, are produced by a biogenesis pathway distinct from microRNAs (miRNAs), which regulate endogenous mRNA expression as guides for Ago1. Here, we report that siRNAs and miRNAs are sorted into Ago1 and Ago2 by pathways independent from the processes that produce these two classes of smal...
متن کاملSorting Out Searching on Small Screen Devices
Small handheld devices – mobile phones, PDAs etc – are increasingly being used to access the Web. Search engines are the most used Web services and are an important user support. Recently, GoogleTM (and other search engine providers) have started to offer their services on the small screen. This paper presents a detailed evaluation of the how easy to use such services are in these new contexts....
متن کاملSorting Out Sound
Speech analysis is a prototypical categorical mechanism that has been examined behaviorally in work going back to Haskins Laboratory studies in the 1950s: such work examined the perception of continua between phonemes and demonstrated sharp discontinuities consistent with categorical perception. In this issue of Neuron, Raizada and Poldrack examine analysis mechanisms for such processing by mea...
متن کاملSorting out Zero-Knowledge
The purpose of this paper is to explain the various notions involved and to offer a new terminology that emphasizes their differences. There are two orthogonal aspects to zero-knowledge interactive proofs. One is the notion of zero-knowledge and the other is the notion of interactive proof. Unfortunately, these two notions are often thought to be inseparable. This confusion is reminiscent of th...
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ژورنال
عنوان ژورنال: Cell
سال: 2008
ISSN: 0092-8674
DOI: 10.1016/j.cell.2008.03.015