Silicon 3D Microdetectors for Microdosimetry in Hadron Therapy
نویسندگان
چکیده
منابع مشابه
Performance of silicon microdosimetry detectors in boron neutron capture therapy.
Reverse-biased silicon p-n junction arrays using Silicon-On-Insulator technology have been proposed as microdosimeters. The performance of such detectors in boron neutron capture therapy (BNCT) is discussed. This work provides the first reported measurements using boron-coated silicon diode arrays as microdosimeters in BNCT. Results are in good agreement with measurements with gas proportional ...
متن کاملTissue equivalence correction for silicon microdosimetry detectors in boron neutron capture therapy.
Reverse-biased silicon p-n junction arrays have been proposed as microdosimetry detectors. The tissue equivalence of such detectors in boron neutron capture therapy (BNCT) is discussed. A comparison of the range-energy relationships of H, He, C, and Li ions in tissue (ICRU-muscle) and silicon is given. A simple geometrical scaling (approximately 0.63) of linear dimensions is required to convert...
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Preclinical studies for boron neutron capture therapy (BNCT) using epithermal neutrons are ongoing at several laboratories. The absorbed dose in tumor cells is a function of the thermal neutron flux at depth, the microscopic boron concentration, and the size of the cell. Dosimetry is therefore complicated by the admixture of thermal, epithermal, and fast neutrons, plus gamma rays, and the array...
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Targeted alpha therapy (TAT) has the advantage of delivering therapeutic doses to individual cancer cells while reducing the dose to normal tissues. TAT applications relate to hematologic malignancies and now extend to solid tumors. Results from several clinical trials have shown efficacy with limited toxicity. However, the dosimetry for the labeled alpha particle is challenging because of the ...
متن کاملA beam monitor using silicon pixel sensors for hadron therapy
We report the design and test results of a beam monitor developed for online monitoring in hadron therapy. The beam monitor uses eight silicon pixel sensors, Topmetal-II−, as the anode array. Topmetal-II− is a charge sensor designed in a CMOS 0.35 μm technology. Each Topmetal-II− sensor has 72 × 72 pixels and the pixel size is 83 × 83 μm. In our design, the beam passes through the beam monitor ...
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ژورنال
عنوان ژورنال: Micromachines
سال: 2020
ISSN: 2072-666X
DOI: 10.3390/mi11121053