Serum levels of CEA and CA 15-3 in triple-negative breast cancer at the time of diagnosis
نویسندگان
چکیده
منابع مشابه
Relationship between preoperative serum CA 15-3 and CEA levels and clinicopathological parameters in breast cancer.
BACKGROUND CEA and CA 15.3 serum tumor markers are currently used in clinical practice for monitoring therapy. The aim of this study was to evaluate serum level of these markers among healthy females and invasive breast carcinoma (IBC) patients and to determine any relationships with clinicopathological factors. MATERIALS AND METHODS 60 Iranian females were enrolled in this study, 30 healthy ...
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Background: Previous data have shown the tumorigenicity roles of HDAC8 in breast cancer. More recently, the oncogenic effects of this molecule have been revealed in TNBC. The present study aimed to determine the diagnostic value of HDAC8 for the differentiation of TNBC from nTNBC tumors. Methods: A total of 50 cancerous and normal adjacent tumor specimens were obtained, and the clinical and pat...
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BACKGROUND Serum HER2 testing allows the determination of real-time HER2 status during clinical course. The aim of this investigation was: (1) to study the prognostic significance of serum HER2 at the time of first diagnosis of metastatic breast cancer and (2) to evaluate its relationship to CA15-3 which is a surrogate marker for tumor load. MATERIALS AND METHODS Serum samples of 120 breast c...
متن کاملSensitivity and Specificity of CA 15-3 in Detection of Breast Cancer Recurrence
Background: The value of CA15-3(cancer antigen 15-3) marker in early detection of breast cancer recurrence has been studied in several prospective trials. But the results of these studies are different. This may be due to variable cutoff points used for analysis, different intervals between CA15-3 measurements and the differences between patients population. This study was done to examine the p...
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ژورنال
عنوان ژورنال: Medical Oncology
سال: 2009
ISSN: 1357-0560,1559-131X
DOI: 10.1007/s12032-009-9310-0