Serotonin 2A receptor gene polymorphism is not associated with completed suicide
نویسندگان
چکیده
منابع مشابه
5-Hydroxytryptamine (serotonin) 2A receptor gene polymorphism is associated with schizophrenia
BACKGROUND & OBJECTIVES Schizophrenia, the debilitating neuropsychiatric disorder, is known to be heritable, involving complex genetic mechanisms. Several chromosomal regions associated with schizophrenia have been identified during the past; putative gene (s) in question, to be called the global signature for the pathophysiology of the disease, however, seems to evade us. The results obtained ...
متن کاملSerotonin 2A receptor gene (HTR2A) polymorphism in alcohol-dependent patients.
BACKGROUND The serotonergic (5-HT) dysfunction has been frequently described in subjects with alcohol dependence (AD). In the present study, a potential relationship between T102C polymorphism in the 5-HT receptor subtype 2Agene (HTR2A) and alcohol dependence was examined. METHODS Genotypes were analyzed in 150 AD patients diagnosed with DSM-IV criteria and in 80 healthy controls. RESULTS T...
متن کاملThe polymorphism of the serotonin-2A receptor T102C is associated with age.
Epidemiological investigations suggest that T102C polymorphism of gene 5-HT2A may be associated with mean life span because diseases and behaviors related to this polymorphism, such as schizophrenia, suicide, aggression, and addiction, may potentially shorten mean life span. A sample of 687 individuals without previous neuropsychiatric disease was genotyped and separated into 3 groups according...
متن کاملIs there an association between T102C polymorphism of the serotonin receptor 2A gene and urinary incontinence?
The regulation of bladder function is influenced by central serotonergic modulation. Several genetic polymorphisms related to serotonin control have been described in the literature. T102C polymorphism of the serotonin receptor 2A gene (5-HT2A) has been shown to be associated with certain diseases such as non-fatal acute myocardial infarction, essential hypertension, and alcoholism. In the pres...
متن کاملPolymorphism in Serotonin Receptor 3B Is Associated with Pain Catastrophizing
Pain catastrophizing, a coping style characterized by excessively negative thoughts and emotions in relation to pain, is one of the psychological factors that most markedly predicts variability in the perception of pain; however, only little is known about the underlying neurobiology. The aim of this study was to test for associations between psychological variables, such as pain catastrophizin...
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ژورنال
عنوان ژورنال: Journal of Psychiatric Research
سال: 2001
ISSN: 0022-3956
DOI: 10.1016/s0022-3956(01)00015-2