Sensitization to the conditioned rewarding effects of morphine modulates gene expression in rat hippocampus
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چکیده
منابع مشابه
Sensitization to the conditioned rewarding effects of morphine modulates gene expression in rat hippocampus.
Opiates addiction is characterized by its long-term persistence. In order to study the enduring changes in long-term memory in hippocampus, a pivotal region for this process, we used suppression subtractive hybridization to compare hippocampal gene expression in morphine and saline-treated rats. Animals were subjected to an extended place preference paradigm consisting of four conditioning phas...
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ژورنال
عنوان ژورنال: Neuropharmacology
سال: 2007
ISSN: 0028-3908
DOI: 10.1016/j.neuropharm.2006.08.012