Selective Serotonin Reuptake Inhibitors for Stroke Recovery
نویسندگان
چکیده
منابع مشابه
Selective serotonin reuptake inhibitors for stroke recovery.
CLINICAL QUESTION Are selective serotonin reuptake inhibitors (SSRIs) associated with better recovery after stroke? BOTTOM LINE SSRIs may be associated with improved recovery after stroke, even in persons without depression. However, much of the evidence is of poor quality. Large, high-quality trials are needed to evaluate the validity of the current evidence and improve precision of estimate...
متن کاملSelective serotonin reuptake inhibitors (SSRIs) for stroke recovery.
BACKGROUND Stroke is the major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression. Recently, small trials have demonstrated that SSRIs might improve recovery after stroke, even in people who are not depressed. Systematic reviews and meta-analyses are the least biased way to bring together data from several trials. Given ...
متن کاملSelective Serotonin Reuptake Inhibitors
It has long been postulated that a deficiency in CNS serotonergic activity is the cause of, or a predisposing factor for, depression. [1] However, the evidence for this association is largely circumstantial and it certainly does not represent an adequate and full model for depression, probably due to there being multiple aetiological factors. [2] Some pharmacological trial data also cast doubt ...
متن کاملSelective serotonin reuptake inhibitors for stroke recovery: a systematic review and meta-analysis.
E ach year, about 16 million people in the world experience a first-ever stroke. Of these, about 5.7 million die and another 5 million remain disabled. 1 Although there are effective treatments that restore brain perfusion and minimize complications and recurrent stroke, there is no treatment proven to facilitate neurological recovery after stroke. A recent small trial demonstrated that the sel...
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ژورنال
عنوان ژورنال: Stroke
سال: 2013
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.112.673947