منابع مشابه
Effective—a database of predicted secreted bacterial proteins
Protein secretion is a key virulence mechanism of pathogenic and symbiotic bacteria, which makes the investigation of secreted proteins ('effectors') crucial for understanding the molecular bacterium-host interactions. Effective (http://effectors.org) is a database of predicted bacterial secreted proteins, implementing two complementary prediction strategies for protein secretion: the identific...
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The Bacteroides fragilis NCTC 9343 genome is the fifth member of the Bacteroidetes/ Chlorobi group to be sequenced and the second Bacteroides fragilis strain. The Bacteroides fragilis NCTC 9343 genome shows considerable variation even within the same strain and ‘invertable promoters’ appear to regulate much of this variance in many surface-exposed and secreted proteins (Cerdeño-Tárraga et al., ...
متن کاملIdentification of secreted bacterial proteins by noncanonical amino acid tagging.
Pathogenic microbes have evolved complex secretion systems to deliver virulence factors into host cells. Identification of these factors is critical for understanding the infection process. We report a powerful and versatile approach to the selective labeling and identification of secreted pathogen proteins. Selective labeling of microbial proteins is accomplished via translational incorporatio...
متن کاملAphids evolved novel secreted proteins for symbiosis with bacterial endosymbiont
Aphids evolved novel cells, called bacteriocytes, that differentiate specifically to harbour the obligatory mutualistic endosymbiotic bacteria Buchnera aphidicola. The genome of the host aphid Acyrthosiphon pisum contains many orphan genes that display no similarity with genes found in other sequenced organisms, prompting us to hypothesize that some of these orphan genes are related to lineage-...
متن کاملInfectious Keratitis: Secreted Bacterial Proteins That Mediate Corneal Damage
Ocular bacterial infections are universally treated with antibiotics, which can eliminate the organism but cannot reverse the damage caused by bacterial products already present. The three very common causes of bacterial keratitis-Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae-all produce proteins that directly or indirectly cause damage to the cornea that can resul...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2001
ISSN: 1474-760X
DOI: 10.1186/gb-2001-2-12-reports0047