SEC-SANS: size exclusion chromatography combinedin situwith small-angle neutron scattering

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SEC-SANS: size exclusion chromatography combined in situ with small-angle neutron scattering1

The first implementation and use of an in situ size exclusion chromatography (SEC) system on a small-angle neutron scattering instrument (SANS) is described. The possibility of deploying such a system for biological solution scattering at the Institut Laue-Langevin (ILL) has arisen from the fact that current day SANS instruments at ILL now allow datasets to be acquired using small sample volume...

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Small angle neutron scattering

Small Angle Neutron Scattering (SANS) is a technique that enables to probe the 3-D structure of materials on a typical size range lying from ∼ 1 nm up to ∼ a few 100 nm, the obtained information being statistically averaged on a sample whose volume is ∼ 1 cm3. This very rich technique enables to make a full structural characterization of a given object of nanometric dimensions (radius of gyrati...

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ژورنال

عنوان ژورنال: Journal of Applied Crystallography

سال: 2016

ISSN: 1600-5767

DOI: 10.1107/s1600576716016514