Research Needs for Bipolar Disorder From Clinicians’ Perspectives: Narrowing the Research–Practice Gap

Goals for research on bipolar disorder: the view from NIMH.

We have much yet to accomplish in research on bipolar disorder. We must find vulnerability genes. We must identify the circuits that regulate mood, emotion, energy, and other relevant functions that are affected in bipolar disorder, and we must determine what goes wrong in those circuits during mania, depression, and other aspects of this illness. We will need to translate findings in basic neu...

Unmet needs of bipolar disorder patients

BACKGROUND Bipolar disorder (BD) is a serious mental illness with adverse impact on the lives of the patients and their caregivers. BD is associated with many limitations in personal and interpersonal functioning and restricts the patients' ability to use their potential capabilities fully. Bipolar patients long to live meaningful lives, but this goal is hard to achieve for those with poor insi...

Narrowing the gap.

Since 1981 AIDS has illuminated, like a roving searchlight, a series of ethical questions, which extend far beyond the apparently narrow limits of one disease. It has revealed, one by one, human attitudes and behaviours that were previously unquestioned, or unobserved based on unidentified but shaky pre-suppositions. This commentary oVers two contrasting perspectives on the problems facing deve...

Narrowing the Nutrition Gap:

Narrowing the 17-Year Research to Practice Gap.

D eveloping evidence to improve clinical practice and disseminating it to be used by clinicians to improve outcomes for individual patients is important. How long does it take to get evidence into practice? The standard refrain of “17 years to move evidence into practice” is repeated by researchers and clinicians alike with despair.1,2 Rather than accepting the inevitability of a long lag in tr...