Relationship of quantitative structure and pharmacokinetics in fluoroquinolone antibacterials
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چکیده
منابع مشابه
Relationship of quantitative structure and pharmacokinetics in fluoroquinolone antibacterials.
AIM To study the relationship between quantitative structure and pharmacokinetics (QSPkR) of fluoroquinolone antibacterials. METHODS The pharmacokinetic (PK) parameters of oral fluoroquinolones were collected from the literature. These pharmacokinetic data were averaged, 19 compounds were used as the training set, and 3 served as the test set. Genetic function approximation (GFA) module of Ce...
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Fluoroquinolone antibacterials: a review on chemistry, microbiology and therapeutic prospects.
Fluoroquinolones are one of the most promising and vigorously pursued areas of contemporary antiinfective chemotherapy depicting broad spectrum and potent activity. They have a relatively simple molecular nucleus, which is amenable to many structural modifications. These agents have several favorable properties such as excellent bioavailability, good tissue penetrability and a relatively low in...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2007
ISSN: 1007-9327
DOI: 10.3748/wjg.v13.i17.2496