Recombinant Human Interleukin-1.ALPHA. Increases Serum Albumin, Gc-Globulin, and .ALPHA.1-Antitrypsin Levels in Burned Mice.
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چکیده
منابع مشابه
Serum Albumin and Globulin
Hundreds of proteins are dissolved in the plasma. By measuring the concentration of these proteins, the clinician can obtain information regarding disease states in different organ systems. The measurement of protein is done on serum, which is the fluid that remains after plasma has clotted, thus removing fibrinogen and most of the clotting factors. Total protein content provides some informati...
متن کاملCausal and Synthetic Associations of Variants in the SERPINA Gene Cluster with Alpha1-antitrypsin Serum Levels
Several infrequent genetic polymorphisms in the SERPINA1 gene are known to substantially reduce concentration of alpha1-antitrypsin (AAT) in the blood. Since low AAT serum levels fail to protect pulmonary tissue from enzymatic degradation, these polymorphisms also increase the risk for early onset chronic obstructive pulmonary disease (COPD). The role of more common SERPINA1 single nucleotide p...
متن کاملThe Albumin/Globulin Ratio in Serum
THE SEPARATION of albumin from its associated globulins in serum or plasma has exercised physiologists and biochemists for many years. Several methods are available for assessing the albumin content of serum by prior precipitation of globulins (1-9). In 1949 Martin and Morris (10) examined a series of methods (1, 2, 5-7) and concluded, by comparison with the results of “free” electrophoresis, t...
متن کاملChanges of Alpha1-Antitrypsin Levels in Allergen-induced Nasal Inflammation
OBJECTIVES Alpha1-antitrypsin (AAT) is the main inhibitor of human neutrophil elastase, and plays a role in counteracting the tissue damage caused by elastase in local inflammatory conditions. The study evaluated the involvement of AAT in nasal allergic inflammation. METHODS Forty subjects with mono-sensitization to Dermatophagoides pteronyssinus (Dpt) were enrolled. Twenty allergic rhinitis ...
متن کاملAlpha1-antitrypsin monotherapy prolongs islet allograft survival in mice.
Islet transplantation for type 1 diabetic patients shows promising results with the use of nondiabetogenic immunosuppressive therapy. However, in addition to compromising the immune system of transplant recipients, long-term studies demonstrate that islet viability is impaired. Here, we demonstrate that, in the absence of immunosuppressive agents, monotherapy with clinical-grade human alpha1-an...
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ژورنال
عنوان ژورنال: The Tohoku Journal of Experimental Medicine
سال: 2002
ISSN: 0040-8727,1349-3329
DOI: 10.1620/tjem.198.23