Recombinant AAV9-TLK1B Administration Ameliorates Fractionated Radiation-Induced Xerostomia
نویسندگان
چکیده
منابع مشابه
Radiation-Induced Xerostomia
Xerostomia is a common complication following radiotherapy for head and neck cancers. This has long-term implications on the quality of life of these patients. The better understanding of salivary function and the interaction of radiotherapy dose-volume and fractionation with salivary function has allowed us to intervene with various modalities to prevent or treat this common complication. Thus...
متن کاملManagement of Radiation Induced Xerostomia
Xerostomia describes both the subjective sensation of oral dryness and the objective reduction in salivary function. Most oncology patients experience oral dryness, at least temporarily during the trajectory of their illness and treatment. In fact, almost all head and neck cancer patients undergoing radiotherapy experience some degree of xersostomia (Chambers, Rosenthal & Weber, 2007). Inadequa...
متن کاملClinical Review Radiation-induced Xerostomia
Background. Radiation-induced xerostomia is a frequent and usually permanent side effect of radiation therapy for head and neck cancer. We summarize recent developments in the prevention and treatment of radiation-induced xerostomia. Methods. The Medline database was searched for articles published within the past 10 years on the prevention and treatment of postirradiation xerostomia. Proceedin...
متن کاملA nursing perspective on radiation-induced xerostomia.
Xerostomia during and following a course of head and neck irradiation profoundly impacts the quality of life of many patients. Xerostomia not only affects mucous membranes and teeth but also interferes with patient comfort, nutrition, and activities of daily living. A thorough evaluation of xerostomia is essential and should include providing anticipatory guidance to the patient and family. In ...
متن کاملReader comments on radiation-induced xerostomia.
I wish to offer comments on “RadiationInduced Xerostomia: How Dry Is Your Patient?” by Susan D. Bruce, RN, BSN, OCN (Vol. 8, pp. 61–67). 1. The author cites dysphasia (multiple times) as an effect of xerostomia. Indeed, difficulty with speech can be a problem. However, dysphagia (difficulty swallowing) is never mentioned in the article. Dysphagia is an almost universal early and late effect of ...
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ژورنال
عنوان ژورنال: Human Gene Therapy
سال: 2013
ISSN: 1043-0342,1557-7422
DOI: 10.1089/hum.2012.235