Reactivity of MIIMetal-Substituted Derivatives of Pig Purple Acid Phosphatase (Uteroferrin) with Phosphate
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چکیده
منابع مشابه
Reactivity of M(II) metal-substituted derivatives of pig purple acid phosphatase (uteroferrin) with phosphate.
The Fe(II) of the binuclear Fe(II)Fe(III) active site of pig purple acid phosphatase (uteroferrin) has been replaced in turn by five M(II) ions (Mn(II), Co(II), Ni(II), Cu(II), and Zn(II)). An uptake of 1 equiv of M(II) is observed in all cases except that of Cu(II), when a second more loosely bound Cu(II) is removed by treatment with edta. The products have been characterized by different anal...
متن کاملDirect electrochemistry of porcine purple acid phosphatase (uteroferrin).
Cyclic voltammetry of the non-heme diiron enzyme porcine purple acid phosphatase (uteroferrin, Uf) has been reported for the first time. Totally reversible one-electron oxidation responses (FeIII-FeII --> FeII-FeIII) are seen both in the absence and in the presence of weak competitive inhibitors phosphate and arsenate, and dissociation constants of these oxoanion complexes formed with uteroferr...
متن کاملTransfer of iron from uteroferrin (purple acid phosphatase) to transferrin related to acid phosphatase activity.
There is continuing controversy as to whether iron can be exchanged from the purple phosphatase, uteroferrin (Uf), to fetal transferrin (Tf) and whether this process might be of physiological relevance during pregnancy in the pig. Here, iron transfer from Uf to apoTf at pH 7.1 was followed by measuring the loss of acid phosphatase activity from native Uf as a function of incubation conditions a...
متن کاملIron transfer between the purple phosphatase uteroferrin and transferrin and its possible role in iron metabolism of the fetal pig.
Uteroferrin, a purple-colored, iron-containing phosphatase which is induced by progesterone in the porcine uterus, has been proposed to be an intermediary in iron transfer between the mother and conceptus in the pig. Along with a number of other uterine proteins of maternal origin, it accumulates in the allantoic fluid during mid-pregnancy. When [59Fe]uteroferrin was introduced into the allanto...
متن کاملFunctional Assessment of an Overexpressed Arabidopsis Purple Acid Phosphatase Gene (Atpap26) in Tobacco Plants
Background: Overexpression of known genes encoding key phosphate (Pi)-metabolizing enzymes, such as acid phosphatases (APases), is presumed to help plants with Pi availability and absorption as they are mostly exposed to suboptimal environmental conditions for this vital element.Objectives: In this study, the overexpression effect of AtPAP26, one of the m...
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ژورنال
عنوان ژورنال: Inorganic Chemistry
سال: 2002
ISSN: 0020-1669,1520-510X
DOI: 10.1021/ic020037f