Proteomics Clinical Applications Reviews 2015
نویسندگان
چکیده
منابع مشابه
Proteomics: from protein structures to clinical applications.
This Symposium is sponsored by: Ruedi Aebersold, ETH Zurich Gary Bader, CCBR, University of Toronto Eleftherios Diamandis, University of Toronto Bruno Domon, Luxembourg Clinical Proteomics Center Andrew Emili, University of Toronto Albert Heck, University of Utrecht Lynn Megeney, Ottawa Hospital Research Institute Peipei Ping, University of California at Los Angeles Juri Rappsilber, University ...
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The completion of the human genome project has marked the official start of the post-genomic era. Due to limitations in DNA and RNA studies, the advent of proteomics, or large-scale analysis of proteins, is considered a crucial consequence and a chief player of post-genomic initiatives. An immediate goal of proteomic studies is the understanding of proteins including their expression, function,...
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Progresses in screening, early diagnosis, prediction of aggressiveness and of therapeutic response or toxicity, and identification of new targets for therapeutic will improve survival of breast cancer. These progresses will likely be accelerated by the new proteomic techniques. In this review, we describe the different techniques currently applied to clinical samples of breast cancer and the mo...
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Expression profiling and proteomics have the potential to transform the management of prostate cancer, identifying new markers for screening, diagnosis, prognosis, monitoring and targets for therapy. Expression profiling has revealed that the majority of prostate cancers contain fusion genes resulting in the upregulation of ETS family transcription factors. New diagnostic markers to replace PSA...
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Proteome versus proteins Each organism contains a single genome in virtually all its cells and thus the difference between the numerous cell types within the same organisms are attributed mainly to genetic imprinting, epigenetics, transcriptional and post-transcriptional processes. Thus studying all the protein molecules present in the living system (termed proteomics) at any given time and phy...
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ژورنال
عنوان ژورنال: PROTEOMICS - Clinical Applications
سال: 2015
ISSN: 1862-8346
DOI: 10.1002/prca.201570015