Protein-protein interactions of human viruses
نویسندگان
چکیده
منابع مشابه
Comparative interactomics for virus–human protein–protein interactions: DNA viruses versus RNA viruses
Viruses are obligatory intracellular pathogens and completely depend on their hosts for survival and reproduction. The strategies adopted by viruses to exploit host cell processes and to evade host immune systems during infections may differ largely with the type of the viral genetic material. An improved understanding of these viral infection mechanisms is only possible through a better unders...
متن کاملDiscovering Domains Mediating Protein Interactions
Background: Protein-protein interactions do not provide any direct information regarding the domains within the proteins that mediate the interactions. The majority of proteins are multi domain proteins and the interaction between them is often defined by the pairs of their domains. Most of the former studies focus only on interacting domain pairs. However they do not consider the in...
متن کاملRabies Infection: An Overview of Lyssavirus-Host Protein Interactions
Viruses are obligatory intracellular parasites that use cell proteins to take the control of the cell functions in order to accomplish their life cycle. Studying the viral-host interactions would increase our knowledge of the viral biology and mechanisms of pathogenesis. Studies on pathogenesis mechanisms of lyssaviruses, which are the causative agents of rabies, have revealed some important ho...
متن کاملdiscovering domains mediating protein interactions
background: protein-protein interactions do not provide any direct information regarding the domains within the proteins that mediate the interactions. the majority of proteins are multi domain proteins and the interaction between them is often defined by the pairs of their domains. most of the former studies focus only on interacting domain pairs. however they do not consider the interaction...
متن کاملIdentification of protein-protein interactions of human HtrA1.
The human heat shock protein HtrA1, a member of the HtrA family of serine proteases, is a evolutionarily highly conserved factor which displays a widespread pattern of expression. The yeast two-hybrid technique was employed to identify new cellular proteins physically interacting with HtrA1, and thus potential targets of this serine protease. An enzymatically inactive HtrA1 point mutant, HtrA1-...
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ژورنال
عنوان ژورنال: Seminars in Cell & Developmental Biology
سال: 2020
ISSN: 1084-9521
DOI: 10.1016/j.semcdb.2018.07.018