Prostaglandin E<sub>2</sub> Inhibits Proteinase-Activated Receptor 2-Signal Transduction through Regulation of Receptor Internalization
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چکیده
منابع مشابه
Prostaglandin E(2) inhibits proteinase-activated receptor 2-signal transduction through regulation of receptor internalization.
Proteinase-activated receptor (PAR) is expressed on various cells, and the PAR family consists of PAR1, PAR2, PAR3, and PAR4. Individual PARs are activated during inflammatory conditions in which they regulate inflammatory responses in various diseases. For example, PAR activation is known to induce prostaglandin E2 (PGE2) production, and then upregulated PGE2 suppresses PAR1 expression in a ne...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 2013
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.12-0365