Promoting Appropriate Antibiotic Use

Promoting Appropriate Use of Drugs in Children

Promotion of appropriate and safe drugs in children is the need of the hour globally. Pediatric population by itself is a spectrum of different physiologies with significant variation in pharmacodynamics and pharmacokinetics. Unfortunately, 50-90% of drugs used in children today have never been actually studied in this population, and the results of drug studies done in adults are often extrapo...

Ecosystem approach to promoting appropriate antibiotic use for children in indigenous communities in Ecuador.

OBJECTIVE To collect baseline data on infectious diseases and antibiotic use in two Andean indigenous communities in Ecuador in order to determine the feasibility and acceptability of applying an ecosystem approach to address associated problems. METHODS In visits to 65 households with children under age 5 years, environmental risk factors for infectious diseases were evaluated through rapid ...

ASP Strategies and Appropriate Antibiotic Use

Rapid diagnostics and appropriate antibiotic use.

Most antibiotics are prescribed by physicians lacking postgraduate training in infectious diseases. As such, prescribing physicians have varying levels of interest and sophistication in thinking about how to use molecular and microbiological data to inform therapeutic choices. Strategies designed to modify physician antimicrobial-prescribing practices must therefore choose simplicity over compl...

Strategies for appropriate antibiotic use in intensive care unit

The comsumption of antibiotics is high, mainly in intensive care units. Unfortunately, most are inappropriately used leading to increased multi-resistant bacteria. It is well known that initial empirical therapy with broad-spectrum antibiotics reduce mortality rates. However the prolonged and irrational use of antimicrobials may also increase the risk of toxicity, drug interactions and diarrhea...