منابع مشابه
Heart hormones fueling a fire in fat
Our view of how adipose tissue metabolism is regulated recently experienced a change in focus and breadth, meaning that some of the key controlling factors were not fully in the picture. The catecholamines of the sympathetic nervous system are well-known activators of β-adrenergic receptors in adipocytes to increase lipolysis. They also drive energy expenditure in brown adipose tissue and, impo...
متن کاملAging and cigarette smoke: fueling the fire.
Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of mortality in North America, accounting for approximately 120,000 of 400,000 total cigarette smoke–related deaths in 2002. COPD preferentially affects elderly individuals, with those 65 or older having 2.6-fold and 35.4-fold higher disease rates than those in the 45 to 64 and 18 to 44 age groups, respectively. Age contri...
متن کاملFueling the fire: Src family kinases drive inflammation
The Src family kinases (SFK) Hck, Fgr, and Lyn are the main SFKs in neutrophils and monocytes. In this issue, in a tour-de-force study of multiple disease models (autoantibody-induced arthritis [K/B×N serum-transfer], skin inflammation induced by systemic administration of collagen VII–specific antibodies, and reverse passive Arthus reaction), Kovacs et al. show that triple knockout (TKO) mice ...
متن کاملInflamed fat: what starts the fire?
Obesity is associated with increased macrophage infiltration of adipose tissue, and these macrophages may be an important component of the chronic inflammatory response playing a crucial role in the development of insulin resistance. This prompts the question as to how macrophages infiltrate obese adipose tissue. In this issue of the JCI, Weisberg et al. show the importance of C-C motif chemoki...
متن کاملBurning Issues with Prometheus - the Canadian Wildland Fire Growth Simulation Model
The software package Prometheus is Canada’s only operational wildfire growth modelling simulator. The program calculates accurate, fast, multi-day forecasts of moving fire fronts and is currently used in fire fighting situations, in fire risk analysis and in the design of “fire-safe” communities and forests. At the core of Prometheus is an algorithm that calculates the evolution of the fire fro...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2004
ISSN: 0270-9139,1527-3350
DOI: 10.1002/hep.20522