منابع مشابه
PAM plus probenecid and procaine penicillin plus probenecid in gonorrhoea.
In 1944, when gonorrhoea responded to 100,000 units of crystalline penicillin given in divided doses, Miller, Scott, and Moeller (1944) observed that the gonococcus was cleared from the urethral secretions within 1 to 6 hours. 23 years later, Holmes, Johnson, and Floyd (1967), in the Far East, noted that only one case, a therapeutic failure, out of twenty treated with 2-4 m.u. procaine penicill...
متن کاملTalampicillin and probenecid compared with ampicillin and probenecid for the treatment of gonococcal urethritis in men.
Two hundred and ten men suffering from uncomplicated gonococcal urethritis were treated with one of two treatment schedules. Of 109 patients treated with 3 g ampicillin and 2 g probenecid (group A) there were two recurrences in the first week after treatment and none in the second week. Of 101 patients treated with 1.5 g talampicillin and 2 g probenecid (group B), there were three recurrences i...
متن کاملAmpicillin plus probenecid compared with procaine penicillin plus probenecid in the treatment of gonorrhoea.
396 male patients with gonococcal urethritis were treated by one of three treatment schedules. Of 132 patients treated with 2.4 m.u. procaine penicillin plus 2 g. probenecid, 109 were followed. There were three (2.8 per cent) recurrences in the first week and none in the second. Of 132 patients treated with 2 g. ampicillin plus 2 g. probenecid, 112 were followed. There were four (3.6 per cent.)...
متن کاملProbenecid, nephrotic syndrome, and renal failure.
Case 1, an electrical engineer, had had recurrent gouty arthritis since the age of 14 years. A paternal uncle had also suffered with gout. From the age of 50 onwards numerous tophi appeared on the hands, feet, elbows, and ears. At one time or another he had been given various drugs, including corticosteroid hormones, phenylbutazone, salicylates, and probenecid. These drugs had produced no harmf...
متن کاملEffect of probenecid on the pharmacokinetics of cefmenoxime.
In this study, we were concerned with the effect of probenecid on the pharmacokinetics of 1,000 mg of cefmenoxime administered over a 30-min period by intravenous infusion. Each of a total of 10 subjects received cefmenoxime twice, once with and once without adjunctive probenecid. The data were fit by iterative nonlinear regression procedures to a two-compartment open pharmacokinetic model, wit...
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ژورنال
عنوان ژورنال: JACC: Case Reports
سال: 2019
ISSN: 2666-0849
DOI: 10.1016/j.jaccas.2019.07.008