Primary hyperparathyroidism-Jaw tumor syndrome: a confusing and forgotten diagnosis

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Primary hyperparathyroidism-jaw tumor syndrome: a confusing and forgotten diagnosis

BACKGROUND Primary hyperparathyroidism is caused by the excessive growth of parathormone secretion, its consequence being hypercalcemia. The parathyroid adenoma is responsible for over half of primary hyperparathyroidism cases. The mandibular tumor can be the initial sign in the case of primary hyperparathyroidism. CASE PRESENTATION We present the case of a 33 year old patient with history of...

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Hyperparathyroidism-jaw tumor syndrome.

BACKGROUND Hyperparathyroidism-jaw tumor (HPT-JT) syndrome is a rare autosomal dominant multiple tumor syndrome characterized by hyperparathyroidism due to single or multiple-gland parathyroid tumor(s). Since it was first described in 1990, the genetics underlying the syndrome have been elucidated and typical clinical presentations are becoming clarified as literature describing this rare entit...

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Hyperparathyroidism-jaw tumor syndrome: a case report.

We report the clinical and genetic findings in a 23-year-old woman with hyperparathyroidism-jaw tumor syndrome (HPT-JT). The patient had a family history of primary hyperparathyroidism (PHPT) and uterine fibroma in her mother. The patient presented muscle weakness. The diagnosis of PHPT was confirmed by an elevated parathyroid hormone level above 1450 pg/ml with hypercalcemia and hypercalciuria...

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Primary hyperparathyroidism in young patients in Russia: high frequency of hyperparathyroidism-jaw tumor syndrome

BACKGROUND Primary hyperparathyroidism (PHPT) is a relatively rare disorder among children, adolescents and young adults. Its development at an early age is suspicious for hereditary causes, though the need for routine genetic testing remains controversial. OBJECTIVE To identify and describe hereditary forms of PHPT in patients with manifestation of the disease under 40 years of age. DESIGN...

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Jaw Tumor: An Uncommon Presenting Manifestation of Primary Hyperparathyroidism Jaw Tumor: An Uncommon Presenting Manifestation of Primary Hyperparathyroidism

Introduction: To report two unusual cases of primary hyperparathyroidism (HPT) that initially manifested with a “ jaw tumor” and to discuss the clinical implications of a giant cell granuloma vs an ossifying fibroma of the jaw. Material and methods: The history, physical examination, laboratory values and the imaging and pathologic findings are described in two patients who presented with a “ja...

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ژورنال

عنوان ژورنال: Medicine and Pharmacy Reports

سال: 2016

ISSN: 2668-0572,2602-0807

DOI: 10.15386/cjmed-638