Pretarsal application of botulinum toxin for treatment of blepharospasm.

Pretarsal application of botulinum toxin for treatment of blepharospasm.

The response to botulinum toxin type A was compared after two injection techniques in 45 patients with blepharospasm. Initially, patients were treated according to a triple injection technique; two injections into the upper eyelid and one injection into the lower eyelid. Subsequently, without altering the dose, the same patient group received two further injections into the pretarsal portion of...

botulinum toxin for treatment of blepharospasm and hemifacial spasm

botulinum toxin produced by clostridium butolinum in one of the most fatal toxins known. botulism is the name given to condition produced by this toxin. in recent years the diluted form of this toxin has been produced in injection form and used for treatment of hemifacial spasm and blepharospasm. this toxin blocks neuromuscular junction and inhibits acetylcholine release. in this article we rep...

Botulinum a toxin treatment of hemifacial spasm and blepharospasm.

We studied the effects of botulinum A toxin in 101 patients with hemifacial spasm and 11 patients with blepharospasm in an open trial and double blind manner. All patients in the open trial and 6 patients in the double blind trial improved after the first injection of botulinum toxin. There was no improvement with placebo. The peak effect ranged from one to 6 days after injection and mean peak ...

Blepharospasm and hemifacial spasm: Long-term treatment with botulinum toxin

Blepharospasm and hemifacial spasm: long-term treatment with botulinum toxin.

INTRODUCTION Our purpose is to describe the demographic, clinical and therapeutic characteristics of patients with blepharospasm (BS) and hemifacial spasm (HFS) in treatment with botulinum toxin type A (BtA). PATIENTS AND METHODS Retrospective analysis of patients diagnosed with BS or HFS and treated with BtA in the Neurology Department at Complejo Asistencial de Segovia between March 1991 an...