Polygenic Mutation in Drosophila melanogaster
نویسندگان
چکیده
منابع مشابه
Polygenic mutation in Drosophila melanogaster: genetic analysis of selection lines.
We have conducted genetic analyses of 12 long-term selection lines of Drosophila melanogaster derived from a highly inbred base population, containing new mutations affecting abdominal and sternopleural bristle number. Biometric analysis of the number of effective factors differentiating the selected lines from the base inbred indicated that with the exception of the three lines selected for in...
متن کاملPolygenic mutation in Drosophila melanogaster: genetic interactions between selection lines and candidate quantitative trait loci.
We have investigated genetic interactions between spontaneous mutations affecting abdominal and sternopleural bristle number that have accumulated in 12 long-term selection lines derived from an inbred strain, and mutations at 14 candidate bristle number quantitative trait loci. The quantitative test for complementation was to cross the selection lines to an inbred wild-type strain (the control...
متن کاملPolygenic mutation in Drosophila melanogaster: non-linear divergence among unselected strains.
A highly inbred strain of Drosophila melanogaster was subdivided into 20 replicate sublines that were maintained independently with 10 pairs of randomly sampled parents per generation for 180 generations. The variance between lines in abdominal and sternopleural bristle number increased little after 100 generations, in contrast to the neutral expectation of a linear increase; and the covariance...
متن کاملPolygenic mutation in Drosophila melanogaster: the causal relationship of bristle number to fitness.
The association between sternopleural and abdominal bristle number and fitness in Drosophila melanogaster was determined for sublines of an initially highly inbred strain that were maintained by divergent artificial selection for 150 generations or by random mating for 180 generations. Replicate selection lines had more extreme bristle numbers than those that were maintained without artificial ...
متن کاملPolygenic mutation in Drosophila melanogaster: Mapping spontaneous mutations affecting sensory bristle number.
Our ability to predict long-term responses to artificial and natural selection, and understand the mechanisms by which naturally occurring variation for quantitative traits is maintained, depends on detailed knowledge of the properties of spontaneous polygenic mutations, including the quantitative trait loci (QTL) at which mutations occur, mutation rates, and mutational effects. These parameter...
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ژورنال
عنوان ژورنال: Genetics
سال: 2005
ISSN: 1943-2631
DOI: 10.1534/genetics.104.032581