Poliomyelitis — epidemiology, molecular biology and immunology

Immunology and Molecular Biology of Protozoan Infections

The protozoan parasites, which cause important diseases affecting million of people worldwide especially in the tropical and subtropical areas, are responsible for high mortality and morbidity. Most of these parasites are transmitted by insect vectors and invade a range of different tissues in their mammalian hosts. Prophylactic and therapeutic strategies are far from satisfactory. Indeed, alth...

Molecular biology and epidemiology of dianthoviruses.

The genus Dianthovirus is one of eight genera in the family Tombusviridae. All the genera have monopartite positive-stranded RNA genomes, except the dianthoviruses which have bipartite genomes. The dianthoviruses are distributed worldwide. Although they share common structural features with the other Tombusviridae viruses in their virions and the terminal structure of the genomic RNAs, the bipa...

Poliomyelitis: its epidemiology and prophylaxis.

IN the history of poliomyelitis we have the story of a disease undergoing a series of transitions with a pattern of evolution which has passed through at least three stages: first, the protracted era of old-fashioned "infantile paralysis," then the terrifying stage of epidemic ccpolio," and finally the present stage, in which paralytic poliomyelitis currently seems to be coming under cont~ol th...

Aptamers as tools in molecular biology and immunology.

We have listed and described recent promising developments in the field of aptamer research. The properties and the application potential of aptamers propose an exciting future for aptamers either in the clinic or as research tools for various purposes. We have reviewed exciting examples in which the SELEX technology was applied to obtain promising tools that may help to facilitate our understa...

Redox Biology and Immunology