Point Mutations in thefolPGene Partly Explain Sulfonamide Resistance ofStreptococcus mutans
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منابع مشابه
Point Mutations in the folP Gene Partly Explain Sulfonamide Resistance of Streptococcus mutans
Cotrimoxazole inhibits dhfr and dhps and reportedly selects for drug resistance in pathogens. Here, Streptococcus mutans isolates were obtained from saliva of HIV/AIDS patients taking cotrimoxazole prophylaxis in Uganda. The isolates were tested for resistance to cotrimoxazole and their folP DNA (which encodes sulfonamide-targeted enzyme dhps) cloned in pUC19. A set of recombinant plasmids carr...
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Background & Objective: Mutations in embB306 gene and their association with resistance to ethambutol (EMB) in Mycobacterium tuberculosis (M. tuberculosis) have not been fully investigated. The aim of this study was to investigate the point-mutations in emb306B gene and their association with resistance to EMB in M. tuberculosis. Materials & Methods: This case (M. tuberculosis resistant to EMB...
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ژورنال
عنوان ژورنال: International Journal of Microbiology
سال: 2013
ISSN: 1687-918X,1687-9198
DOI: 10.1155/2013/367021