PLCE1 Polymorphism and Upper Gastrointestinal Cancer Risk: A Meta-Analysis
نویسندگان
چکیده
منابع مشابه
PLCE1 Polymorphism and Upper Gastrointestinal Cancer Risk: A Meta-Analysis
BACKGROUND In recent years, the PLCE1 rs2274223 polymorphism has been extensively investigated as a potential risk factor for upper gastrointestinal cancers, including squamous cell carcinoma (ESCC) and gastric cancer. However, the results of these studies have been inconsistent. METHODS A meta-analysis of 13 case-control studies was performed including more than 11,000 subjects with genotype...
متن کاملAssociation between PLCE1 rs2274223 A > G polymorphism and cancer risk: proof from a meta-analysis
UNLABELLED Phospholipase C epsilon 1 (PLCE1) plays an important role in cell growth, differentiation and oncogenesis. An increasing number of individual studies have investigated the association between PLCE1 rs2274223 polymorphism and cancer risk, but the conclusions are inconclusive. To obtain a comprehensive conclusion, we performed a meta-analysis of 22 studies with 13188 cases and 14666 co...
متن کاملPLCE1 rs2274223 polymorphism and risk of gastric cancer: a meta-analysis based on 14 publications
Background: PLCE1 rs2274223 polymorphism is reportedly associated with gastric cancer. However, focusing on various populations or other different elements, these published articles provided diverging results, so a meta-analysis was needed under such a circumstance. Methods: Odds ratios (ORs) with corresponding 95% confidence intervals (95% CIs) were employed to assess the association between P...
متن کاملAssociation between STAT3 rs1053004 polymorphism and cancer risk: a meta-analysis
Several studies examined the relationship between STAT3 rs1053004 polymorphism and the risk of some human cancers, but the findings remains inconclusive. To evaluate the impact of STAT3 rs1053004 on cancer risk, we conducted a meta-analysis of all available studies including 4,605 cancer cases and 5,248 controls. Eligible studies were identified by searching PubMed, Web of Sci...
متن کاملRs401681 polymorphism in TERT-CLPTM1L was associated with bladder cancer risk: A meta-analysis
Objective(s):Genome-wide association studies have identified a number of genetic variants of telomerase reverse transcriptase (TERT), cleft lip and palate transmembrane1-like (CLPTM1L) associated with the risk of bladder cancer. Rs401681 polymorphism in TERT-CLPTM1L was of special interest for bladder cancer risk, whereas the results were inconclusive. Materials and Methods:Publications illustr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0067229