Placental growth factor supports neuroendocrine tumor growth and predicts disease prognosis in patients
نویسندگان
چکیده
منابع مشابه
Placental Growth Factor
Preeclampsia, a pregnancy-related condition characterized by hypertension and proteinuria after 20 weeks of gestation, is an enormous global health problem. It is a major cause of maternal and neonatal morbidity and mortality and is closely linked to fetal growth retardation. Moreover, preeclampsia heralds an elevated risk of cardiovascular disease for both the mother and the baby in later life...
متن کاملPlacental Growth Factor
Preeclampsia, a pregnancy-related condition characterized by hypertension and proteinuria after 20 weeks of gestation, is an enormous global health problem. It is a major cause of maternal and neonatal morbidity and mortality and is closely linked to fetal growth retardation. Moreover, preeclampsia heralds an elevated risk of cardiovascular disease for both the mother and the baby in later life...
متن کاملVascular endothelial growth factor-dependent spatiotemporal dual roles of placental growth factor in modulation of angiogenesis and tumor growth.
Placental growth factor (PlGF) remodels tumor vasculatures toward a normalized phenotype, which affects tumor growth, invasion and drug responses. However, the coordinative and spatiotemporal relation between PlGF and VEGF in modulation of tumor angiogenesis and vascular remodeling is less understood. Here we report that PlGF positively and negatively modulate tumor growth, angiogenesis, and va...
متن کاملEvaluation of Periodontal Disease Effect on the Expression of Vascular Endothelial Growth Factor and Nerve Growth Factor in Dental Pulp
Introduction: Researchers have always been interested in the close and mutual relationship between the pulp and periodontal tissues. Although the effects of pulpal disease on periodontium have been well known, the clear relationship between periodontitis and pulp has not been documented . It seems that bacteria and inflammatory products of periodontitis can affect pulp through accessory canals,...
متن کاملDecreased expression of LKB1 predicts poor prognosis in pancreatic neuroendocrine tumor patients undergoing curative resection
Background Liver kinase B1 (LKB1) is a key regulatory protein of cellular metabolism, proliferation, and polarity. The present study aimed to characterize the expression pattern of LKB1 in pancreatic neuroendocrine tumors (pNETs) and evaluate the relationship between LKB1 expression and prognosis in pNETs. Patients and methods We retrospectively analyzed the pathologic and clinical data of 71...
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ژورنال
عنوان ژورنال: Endocrine-Related Cancer
سال: 2013
ISSN: 1351-0088,1479-6821
DOI: 10.1530/erc-12-0223