Pharmacokinetic aspects of dose-response relationship
نویسندگان
چکیده
منابع مشابه
Dose-response relationship of phototherapy for hyperbilirubinemia.
BACKGROUND AND OBJECTIVE Using light-emitting diodes during conventional phototherapy, it is possible to reduce the distance from light source to infant, thus increasing light irradiance. The objective of this study was to search for a "saturation point" (ie, an irradiation level above which there is no further decrease in total serum bilirubin [TsB]). This was a prospective randomized study pe...
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PURPOSE Cancer induction after radiation therapy is known as a severe side effect. It is therefore of interest to predict the probability of second cancer appearance for the patient to be treated including breast cancer. MATERIALS AND METHODS In this work a dose-response relationship for breast cancer is derived based on(i) the analysis of breast cancer induction after Hodgkin's disease,(ii) ...
متن کاملDose-response relationship in multistage carcinogenesis: promoters.
Published dose-response curves of promoters of multistage carcinogenesis were selected that met the combined criteria of long study times, multiple doses, and low doses. In rat liver, 12 dose-response studies of 7 different promoters (phenobarbital, 2,3,7,8-tetrachlorodibenzo-p-dioxin [TCDD], clophen A-50 (a polychlorinated biphenyl), alpha-, beta-, and gamma-hexachlorocyclohexane [HCH], and ch...
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36 clients with anxiety neurosis were trained to reduce frontalis muscle tension over two phases of ten sessions each. They were assessed on psychological and physiological measures, before, during and after the phases. The data analysis indicated that the clients succeeded in lowering frontalis muscle tension levels during the feedback and no-feedback phases of the training sessions. The inter...
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Background: The electrical dose selected for electroconvulsive therapy (ECT) must have an acceptable efficacy and no or minimal cognitive side-effects. We evaluated the clinical efficacy and cognitive side-effects of ECT in relation to the stimulus dose administered. Method: This study assessed 71 depressed patients who were treated with bilateral ECT. For evaluation of depressive and cognitive...
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ژورنال
عنوان ژورنال: Japanese Journal of Biometrics
سال: 1996
ISSN: 2185-6494,0918-4430
DOI: 10.5691/jjb.17.s31