Perioperative opioid requirements of patients receiving sublingual buprenorphine-naloxone: a case series

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Buprenorphine implants for treatment of opioid dependence: randomized comparison to placebo and sublingual buprenorphine/naloxone.

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New developments in the management of opioid dependence: focus on sublingual buprenorphine–naloxone

Opioid maintenance therapy is a well-established first-line treatment approach in opioid dependence. Buprenorphine, a partial opioid agonist, has been found by numerous studies to be an effective and safe medication in the treatment of opioid dependence. At present, buprenorphine is available as a monodrug or in a fixed 4:1 ratio combination with naloxone. A diminished risk of diversion and abu...

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PURPOSE Sublingual buprenorphine and combination buprenorphine/naloxone (BNX) are effective options for the treatment of opioid dependence. A BNX sublingual tablet approved by the US Food and Drug Administration for the induction and maintenance treatment of opioid-dependence in adults was developed as a higher-bioavailability formulation, allowing for a 30% lesser dose of buprenorphine with bi...

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ژورنال

عنوان ژورنال: BMC Anesthesiology

سال: 2019

ISSN: 1471-2253

DOI: 10.1186/s12871-019-0745-3