PBP2a substitutions linked to ceftaroline resistance in MRSA isolates from the UK: Table 1.
نویسندگان
چکیده
منابع مشابه
PBP2a substitutions linked to ceftaroline resistance in MRSA isolates from the UK.
Department of Medicine, University of Cambridge, Cambridge, UK; Department of Veterinary Medicine, University of Cambridge, Cambridge, UK; Clinical Microbiology and Public Health Laboratory, Public Health England, Cambridge, UK; Royal Veterinary College, Hawkshead Campus, University of London, London, UK; Antimicrobial Resistance and Healthcare Associated Infections Reference Unit, Public Healt...
متن کاملA small Acinetobacter plasmid carrying the tet39 tetracycline resistance determinant
mediate ceftaroline resistance (Table 1). Two isolates (ASARM167 and A38) belonging to ST22 (epidemic MRSA-15) had an E239K substitution in PBP2a. ASARM167 was isolated from a patient with bacteraemia at Cambridge University Hospitals NHS Foundation Trust (CUH) in 2008 and A38 was isolated from a canine wound infection in 2006 treated in Wiltshire, southwest England. 8 Phylogenetic analysis of ...
متن کاملMolecular characterization of MRSA isolates bracketing the current EUCAST ceftaroline-susceptible breakpoint for Staphylococcus aureus: the role of PBP2a in the activity of ceftaroline.
OBJECTIVES The objectives of this study were to characterize contemporary MRSA isolates and understand the prevalence and impact of sequence variability in PBP2a on ceftaroline susceptibility. METHODS A total of 184 MRSA isolates collected from 28 countries were collected and characterized. RESULTS WT PBP2a proteins were found in MRSA distributed evenly over the ceftaroline MIC range of 0.5...
متن کاملAntimicrobial activity of Ceftaroline and Ceftobiprole tested against MRSA isolates from Turkey, in 2016
Ceftaroline and ceftobiprole are two new cephalosporin molecules on which intense studies have been made for the treatments of bacteria most of which are hospital infection factor, especially resistant gram positive cocci. Ceftaroline which has broad Gram-positive activity recently has been approved for clinical uses by the US Food and Drug Administration. Ceftobiprole has been approved for use...
متن کاملfrom linguistics to literature: a linguistic approach to the study of linguistic deviations in the turkish divan of shahriar
chapter i provides an overview of structural linguistics and touches upon the saussurean dichotomies with the final goal of exploring their relevance to the stylistic studies of literature. to provide evidence for the singificance of the study, chapter ii deals with the controversial issue of linguistics and literature, and presents opposing views which, at the same time, have been central to t...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2015
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dkv317