PARAMYXOVIRUS PHYLOGENY: TISSUE TROPISM EVOLVES SLOWER THAN HOST SPECIFICITY
نویسندگان
چکیده
منابع مشابه
Envelope targeting: hemagglutinin attachment specificity rather than fusion protein cleavage-activation restricts Tupaia paramyxovirus tropism.
To engineer a targeting envelope for gene and oncolytic vector delivery, we characterized and modified the envelope proteins of Tupaia paramyxovirus (TPMV), a relative of the morbilli- and henipaviruses that neither infects humans nor has cross-reactive relatives that infect humans. We completed the TPMV genomic sequence and noted that the predicted fusion (F) protein cleavage-activation site i...
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ژورنال
عنوان ژورنال: Evolution
سال: 1990
ISSN: 0014-3820,1558-5646
DOI: 10.1111/j.1558-5646.1990.tb05210.x