PAMPs/DAMPs as novel mediators of inflammation-associated thrombosis
نویسندگان
چکیده
منابع مشابه
Interleukin 6 regulates psoriasiform inflammation-associated thrombosis.
Psoriasis patients are at increased risk of heart attack and stroke and have elevated MRP8/14 levels that predict heart attack. The KC-Tie2 psoriasiform mouse model exhibits elevated MRP8/14 and is prothrombotic. Mrp14-/- mice, in contrast, are protected from thrombosis, but, surprisingly, KC-Tie2xMrp14-/- mice remain prothrombotic. Treating KC-Tie2xMrp14-/- mice with anti-IL-23p19 antibodies r...
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ژورنال
عنوان ژورنال: Japanese Journal of Thrombosis and Hemostasis
سال: 2013
ISSN: 0915-7441,1880-8808
DOI: 10.2491/jjsth.24.675