Overview of nanogel and its applications
نویسندگان
چکیده
Nanogel have emerged as a versatile drug delivery system for encapsulation of guest molecules. A nanoparticle which is composed hydrophilic polymer network known having range from 100-200nm. swellable and degradation properties with high loading capacity, stability, sustained targetable manner, large surface area. Therefore, nanogel are more productive than conventional micro-sized delivery. In recent year in the field biotechnology were prominently used to deal genetics, enzyme immobilization protein synthesis. Moreover, it has asset development novel therapeutic medicine. These soft materials capable holding small molecular biomacromolecules, therapeutics, inorganic nanoparticles within their crosslinked networks, allows them find applications therapy well imaging variety disease conditions. not only enhance functionality carrier but also help overcoming many challenges associated cargo This review aims highlight distinct unique capabilities nanogels system, Synthesis nanogels, Types Physical chemical Stimuli responsive behavior, vivo Therapeutic carrier, marketed formulation Nanogels last part summarizes various diseases. Transdermal delivery, diabetes, anti-inflammatory, vaginal neurodegenerative diseases, ocular dieses, autoimmune disease, anticancer treatment specially targeting cancer cells, thereby reducing uptake into healthy cells. phenomenal further depth study required explore interaction at cellular levels minimize challenges.
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ژورنال
عنوان ژورنال: GSC biological and pharmaceutical sciences
سال: 2021
ISSN: ['2581-3250']
DOI: https://doi.org/10.30574/gscbps.2021.16.1.0196