منابع مشابه
Suitability of limited sampling strategy to cyclosporine A oral formulation.
Therapeutic drug monitoring of cyclosporine A in renal transplant patients is normally performed by measuring pre-dose trough levels or doing area under the curve profiles from all possible sampling points. On the basis of good correlation between predicted area under the curve from limited sampling points and actual area under the curve (literature survey), a limited sampling strategy at 1, 3 ...
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The efficacy of chemoprevention trials can be improved by the use of biomarkers of carcinogenesis that serve as surrogate end points. The aim of this study was to assess the perspectives of using mRNA isolated from oral exfoliated cells for biomarker research in chemoprevention of upper aerodigestive tract cancer. When using reverse transcription-PCR in combination with Southern blotting and hy...
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Drug testing is increasingly used in the screening of applicants for employment. Despite the growth of drug testing, there is little research that examines the value of pre-employment drug-use information in the prediction of post-employment suitability. This research, which was based on a sample of 10,i88 young adults, examined the criterion-related validity of pre-employment drug-use informat...
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Agilent Captiva Premium syringe filters were tested thoroughly for sample preparation in drug assays. The potential impact on drug binding through filtration was evaluated based on analyte recovery. Five representative drugs were selected, covering a wide variety of chemical and physical properties and drug binding propensity. All of the tests were performed following USP (United States Pharmac...
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Chronic hepatitis C virus infection is a common and serious disease. Although an estimated 2.7 million persons in the United States have this disease, most have not yet been diagnosed. Recent advances in treatment provide successful cure in 50 to 80 percent of cases. Current drug therapy consists of a combination of pegylated interferon and ribavirin. Although all patients with chronic hepatiti...
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ژورنال
عنوان ژورنال: MedChemComm
سال: 2018
ISSN: 2040-2503,2040-2511
DOI: 10.1039/c7md00586e