Omalizumab Facilitates Rapid Oral Desensitization for Peanut Allergy
نویسندگان
چکیده
منابع مشابه
Successful oral desensitization for systemic peanut allergy.
To the Editor: The present strategy of avoidance and epinephrine autoinjection for severe IgE-mediated food reactions is not always successful.1,2 This may be even truer for young children, who cannot read and have to depend on adults to administer the epinephrine. The following case report illustrates such a failure in a young child and describes a treatment that can be performed by an allergy...
متن کاملA pilot study of omalizumab to facilitate rapid oral desensitization in high-risk peanut-allergic patients.
BACKGROUND Peanut allergy is a major public health problem that affects 1% of the population and has no effective therapy. OBJECTIVE To examine the safety and efficacy of oral desensitization in peanut-allergic children in combination with a brief course of anti-IgE mAb (omalizumab [Xolair]). METHODS We performed oral peanut desensitization in peanut-allergic children at high risk for devel...
متن کاملOmalizumab as successful treatment option in severe peanut allergy
Methods We present the case of a girl, who was diagnosed with peanut allergy at age 8 after she developed abdominal pain, urticaria and angioedema following a meal of cornflakes with peanut chips. No food challenge was performed at that time, and she was advised to avoid peanuts. Despite avoiding foods visibly containing peanut, she repeatedly experienced urticaria, burning of the tongue, nause...
متن کاملImmunotherapy for peanut allergy.
Peanut allergy is one of the commonest food hypersensitivities causing fatal or near-fatal reactions. There is, currently, no preventive treatment and the incidence of severe allergic reactions during peanut desensitisation has limited its clinical use. Anti-immunoglobulin E therapy has been shown to be effective in preventing peanut-induced reactions but it does not result in long-term toleran...
متن کاملSuccessful desensitization in a boy with severe cow’s milk allergy by a combination therapy using omalizumab and rush oral immunotherapy
BACKGROUND Rush oral immunotherapy (OIT) combined with omalizumab (OMB) has been reported to be an effective and safe treatment for severe milk allergies. However, no report has described long-term follow-up observations after OMB discontinuation. The purpose of this case report was to evaluate the safety and efficacy of rush OIT in combination with OMB during a long period of treatment. CASE...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2016
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2015.12.766