NPY+-, but not PV+-GABAergic neurons mediated long-range inhibition from infra- to prelimbic cortex
نویسندگان
چکیده
منابع مشابه
Long-range GABAergic neurons in the prefrontal cortex modulate behavior.
Cortical glutamatergic projections are extensively studied in behavioral neuroscience, whereas cortical GABAergic projections to downstream structures have been overlooked. A recent study by Lee and colleagues (Lee AT, Vogt D, Rubenstein JL, Sohal VS. J Neurosci 34: 11519-11525, 2014) used optogenetic and electrophysiological techniques to characterize a behavioral role for long-projecting GABA...
متن کاملLong-range-projecting GABAergic neurons modulate inhibition in hippocampus and entorhinal cortex.
The hippocampus and entorhinal cortex play a pivotal role in spatial learning and memory. The two forebrain regions are highly interconnected via excitatory pathways. Using optogenetic tools, we identified and characterized long-range γ-aminobutyric acid-releasing (GABAergic) neurons that provide a bidirectional hippocampal-entorhinal inhibitory connectivity and preferentially target GABAergic ...
متن کاملNeuro Forum Long-range GABAergic neurons in the prefrontal cortex modulate behavior
Bravo-Rivera C, Diehl MM, Roman-Ortiz C, Rodriguez-Romaguera J, Rosas-Vidal LE, Bravo-Rivera H, Quiñones-Laracuente K, DoMonte FH. Long-range GABAergic neurons in the prefrontal cortex modulate behavior. J Neurophysiol 114: 1357–1359, 2015. First published December 17, 2014; doi:10.1152/jn.00861.2014.—Cortical glutamatergic projections are extensively studied in behavioral neuroscience, whereas...
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We examined effects of botulinum neurotoxin A (BoNTA) on sympathetic constrictions of the vena cava and uterine artery from guinea pigs to test the role of soluble NSF attachment protein receptor (SNARE) proteins in release of the cotransmitters norepinephrine (NE) and neuropeptide Y (NPY). Protein extracts of venae cavae and uterine arteries showed partial cleavage of synaptosomal associated p...
متن کاملActivity in prelimbic cortex is necessary for the expression of learned, but not innate, fears.
The amygdala has long been considered to be both necessary and sufficient for classical fear conditioning, but recent evidence suggests that the medial prefrontal cortex (mPFC) may also be involved. The prelimbic (PL) subregion of mPFC projects to the amygdala, and neurons in PL show fear-related increases in activity. It is unknown, however, whether PL activity is necessary for expression of l...
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ژورنال
عنوان ژورنال: Translational Psychiatry
سال: 2016
ISSN: 2158-3188
DOI: 10.1038/tp.2016.7