Non-invasive bronchial epithelial papillary tumors

[Non-invasive follicular thyroid neoplasm with papillary-like nuclear features].

Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was introduced to cover a group of noninvasive encapsulated follicular-patterned thyroid lesions with very low malignant behavior. This nomination may have a great impact on the incidence of thyroid malignancy and the practice for endocrine pathologists. To demonstrate the proportion of the thyroid follicular ...

Invasive Papillary Breast Carcinoma

We present the case of a 55-year-old postmenopausal female who presented with complaints of a gradually increasing painless subareolar mass in the left breast of 4 months' duration. Left-sided modified radical mastectomy was performed and the specimen was histopathologically diagnosed as invasive papillary carcinoma. Immunohistochemistry confirmed this diagnosis. All 8 excised axillary lymph no...

Bronchial Neuroendocrine Tumors

Mesenchymal (non-epithelial) "non-GIST" tumors of the digestive tract.

Morphological, immunohistochemical and ultrastructural but also clinical and prognostic differences between multiple types of mesenchimal (stromal, nonepithelial) tumors of the gastrointestinal tract prompted us the remembrance of an anecdotic series of sixteen observations of mesenchymal "nonstromal" gastrointestinal tumors (MNSGIT) encountered in four decades of surgical practice. The diagnos...

A 3 D culture model and computer - assisted videomicroscopy for analyzing the migratory behavior of non invasive and invasive bronchial epithelial cells

To date, most of the studies in the field of cell migration were applied to two dimensional models. To mimic the three dimensional (3D) conditions similar to those observed in vivo during tumor invasion, we developed a 3D model of cell migration in which cells were embedded in a collagen I matrix placed in a double compartment chamber. Using time lapse videomicroscopy and interactive cell track...