Non-homogenous Poisson Process for Evaluating Stage I & II Ductal Breast Cancer Treatment

Non-homogenous Poisson Process for Evaluating Stage I & II Ductal Breast Cancer Treatment

Immunotherapy for Breast Cancer Treatment

Breast cancer, as a heterogeneous disease, includes a wide range of pathological and clinical behaviors. Current treatment protocols, including radiotherapy, chemotherapy, and hormone replacement therapy, are mainly associated with poor response and high rate of recurrence. Therefore, more efforts are needed to develop alternative therapies for this type of cancer. Immunotherapy, as a novel str...

Stage II breast cancer

Stage II breast cancer is further subdivided into stages IIA and IIB. Patients classified as having stage IIA breast cancer include those with T0-1, N1, and T2, N0 disease. Stage IIB breast cancer includes patients with T2, N1, and T3, N0 disease. Therefore, this patient population is more heterogeneous than the populations with stage 0 and stage I disease. The pretreatment evaluation and type ...

Non-Surgical Breast-Conserving Treatment (KORTUC-BCT) Using a New Radiosensitization Method (KORTUC II) for Patients with Stage I or II Breast Cancer

The purpose of the present study was to establish a non-surgical breast-conserving treatment (BCT) using KORTUC II radiosensitization treatment. A new radiosensitizing agent containing 0.5% hydrogen peroxide and 0.83% sodium hyaluronate (a CD44 ligand) has been developed for intra-tumoral injection into various tumors. This new method, named KORTUC II, was approved by our local ethics committee...

Estimation of Parameters of the Power-Law-Non-Homogenous Poisson Process in the Case of Exact Failures Data

  This expository article shows how the maximum likelihood estimation method and the Newton-Raphson algorithm can be used to estimate the parameters of the power-law Poisson process model used to analyze data from repairable systems .