Neuroprotective Effect of Melissa officinalis in Animal Model of Spinal Cord Injurya

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چکیده

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Coadministration of Dexamethasone and Melissa officinalis Has Neuroprotective Effects in Rat Animal Model with Spinal Cord Injury

OBJECTIVE Spinal cord injury (SCI) causes inflammation, deformity and cell loss. It has been shown that Melissa officinalis (MO), as herbal medicine, and dexamethasone (DEX) are useful in the prevention of various neurological diseases. The present study evaluated combinational effects of DEX and MO on spinal cord injury. MATERIALS AND METHODS Thirty six adult male Wistar rats were used in th...

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coadministration of dexamethasone and melissa officinalis has neuroprotective effects in rat animal model with spinal cord injury

objective: spinal cord injury (sci) causes inflammation, deformity and cell loss. it has been shown that melissa officinalis (mo), as herbal medicine, and dexamethasone (dex) are useful in the prevention of various neurological diseases. the present study evaluated combinational effects of dex and mo on spinal cord injury. materials and methods: thirty six adult male wistar rats were used in th...

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Assessment of Neuroprotective Properties of Melissa officinalis in Combination With Human Umbilical Cord Blood Stem Cells After Spinal Cord Injury

INTRODUCTION The pathophysiology of spinal cord injury (SCI) has a classically bad prognosis. It has been demonstrated that human umbilical cord blood stem cells (hUCBSCs) and Melissa officinalis (MO) are useful for the prevention of neurological disease. METHODS Thirty-six adult male rats were randomly divided into intact, sham, control (SCI), MO, hUCBSC, and MO-hUCBSC groups. Intraperitonea...

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Potential neuroprotective effect of Anakinra in spinal cord injury in an in vivo experimental animal model

OBJECTIVE To evaluate the therapeutic effects of inhibiting interleukin-1 beta (IL-1 beta) in vivo using Anakinra in an experimental model of spinal cord injury (SCI). METHODS All experimental procedures were performed in the animal laboratory of Ankara Education and Research Hospital, Ankara, Turkey between August 2012 and May 2014. The SCI was induced by applying vascular clips to the dura ...

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W5: Animal Models of Spinal Cord Injury

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ژورنال

عنوان ژورنال: Medicinal & Aromatic Plants

سال: 2015

ISSN: 2167-0412

DOI: 10.4172/2167-0412.s1-004