Neurite orientation dispersion and density imaging (NODDI) and free‐water imaging in Parkinsonism
نویسندگان
چکیده
منابع مشابه
NODDI: Practical in vivo neurite orientation dispersion and density imaging of the human brain
This paper introduces neurite orientation dispersion and density imaging (NODDI), a practical diffusion MRI technique for estimating the microstructural complexity of dendrites and axons in vivo on clinical MRI scanners. Such indices of neurites relate more directly to and provide more specific markers of brain tissue microstructure than standard indices from diffusion tensor imaging, such as f...
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Background: Presurigical planning for glioma tumor resection and radiotherapy treatment require proper delineation of tumoral and peritumoral areas of brain. Diffusion tensor imaging (DTI) is the most common mathematical model applied for diffusion weighted MRI data. Neurite orientation dispersion and density imaging (NODDI) is another mathematical model for DWI data modeling.Objective: We stud...
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Increased hyperphosphorylated tau and the formation of intracellular neurofibrillary tangles are associated with the loss of neurons and cognitive decline in Alzheimer's disease, and related neurodegenerative conditions. We applied two diffusion models, diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI), to in vivo diffusion magnetic resonance images (...
متن کاملUnderstanding microstructure of the brain by comparison of neurite orientation dispersion and density imaging (NODDI) with transparent mouse brain
BACKGROUND Neurite orientation dispersion and density imaging (NODDI) is a diffusion magnetic resonance imaging (MRI) technique with the potential to visualize the microstructure of the brain. Revolutionary histological methods to render the mouse brain transparent have recently been developed, but verification of NODDI by these methods has not been reported. PURPOSE To confirm the concordanc...
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Human aging is accompanied by progressive changes in executive function and memory, but the biological mechanisms underlying these phenomena are not fully understood. Using neurite orientation dispersion and density imaging, we sought to examine the relationship between age, cellular microstructure, and neuropsychological scores in 116 late middle-aged, cognitively asymptomatic participants. Re...
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ژورنال
عنوان ژورنال: Human Brain Mapping
سال: 2019
ISSN: 1065-9471,1097-0193
DOI: 10.1002/hbm.24760