Neural Mechanisms of Paroxysmal Atrial Fibrillation and Paroxysmal Atrial Tachycardia in Ambulatory Canines

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Neural mechanisms of paroxysmal atrial fibrillation and paroxysmal atrial tachycardia in ambulatory canines.

BACKGROUND The relationship between autonomic activation and the mechanisms of paroxysmal atrial fibrillation remains unclear. METHODS AND RESULTS We implanted a pacemaker and a radio transmitter in 7 dogs (group 1). After baseline recording, we paced the left atrium at 20 Hz for 1 week and then monitored left stellate ganglion nerve activity, left vagal nerve activity, and left atrial electr...

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Canine model of paroxysmal atrial fibrillation and paroxysmal atrial tachycardia.

Both autonomic nerve activity and electrical remodeling are important in atrial arrhythmogenesis. Therefore, dogs with sympathetic hyperinnervation, myocardial infarction (MI), and complete atrioventricular block (CAVB) may have a high incidence of atrial arrhythmias. We studied eight dogs (experimental group) with MI, CAVB, and sympathetic hyperinnervation induced either by nerve growth factor...

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Polyuria in Paroxysmal Tachycardia and Paroxysmal Atrial Flutter and Fibrillation.

When Paul Wood spoke about this to the British Cardiac Society in 1961, we were impressed by the originality of his work on a subject that so many had noticed but failed to investigate. A few months before his death in July 1962, when I asked him if his paper was ready for the journal, he said that he had not yet been able to get all the evidence he hoped for to establish the full explanation. ...

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Paroxysmal Atrial Fibrillation Prediction Using Isolated Premature Atrial Events and Paroxysmal Atrial Tachycardia

A simplified predictor of episodes of paroxysmal atrial fibrillation (PAF) is presented. Over a thirty minute monitoring time, the number of premature atrial complexes (PAC) without normal sinus node reset is counted. When the number of such PACs changes by more than 2 over the monitoring period, a PAF prediction is made. The PAC test is supplemented with a paroxysmal atrial tachycardia (PAT) t...

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Congenital paroxysmal atrial tachycardia.

Ten infants who had paroxysmal atrial tachycardia in utero or at birth are reported. Because of apparent fetal distress, caesarean section was performed in 4 cases and labour was induced in 1. Birthweight was generally large for gestational age. Severe ascites and hydrops at birth were manifestations of cardiac failure. Atrial flutter was recorded in 4 infants and supraventricular tachycardia i...

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ژورنال

عنوان ژورنال: Circulation

سال: 2008

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.108.776203